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Preclinical Data—Biomerix RCR Patch™

The Biomerix RCR Patch material properties and three dimensional open architecture is designed to facilitate rapid, fibrovascular tissue ingrowth providing a durable healing response throughout the entire reparative process.

Designed to facilitate rapid fibrocollagenous tissue ingrowth to support the remodeling process for tendon to bone healing

  • Preclinical results in a rat supraspinatus tendon model demonstrated a high degree of collagenous and fibrovascular tissue infiltration into the porous scaffold, indicative of a rapid healing response and penetration by native fibrovascular tissue by the two-month time point. Reparative tissue growth within the Biomerix RCR Patch was well-integrated into the tendon of the supraspinatus.
  • Results also indicated no signs of significant inflammation and scar tissue formation, indicative of a successful repair process in a challenging anatomic site
  • In an ovine chronic supraspinatus tendon tear model, the Biomerix RCR Patch demonstrated statistically significant increases in failure force (74%) and failure stress (95%) when compared to surgical control animals at the three-month time point.2
  • 1 Cole et al., "Biocompatibility of a polymer patch for rotator cuff repair," Knee Surg Sports Tramatol Arthrosc (2007); 15(5):632-637.
  • 2 1. Jost, B., et al. "Clinical outcomes after structural failure of rotator cuff repairs," Journal of Bone and Joint Surgery — American edition (2000), 82:304-314. Data on file with

The Biomaterial Story

Learn how the Biomerix Biomaterial's three-dimensional, open-cell architecture is constructed to allow for tissue ingrowth throughout its interconnected macroporous structure.
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