Preclinical Data | Biomerix RCR Patch™
The Biomerix RCR Patch™ material properties and three dimensional open architecture is designed to facilitate rapid, fibrovascular tissue ingrowth providing a durable healing response throughout the entire reparative process.
Designed to facilitate rapid fibrocollagenous tissue ingrowth to support the remodeling process for tendon to bone healing
- Preclinical results in a rat supraspinatus tendon model demonstrated
a high degree of collagenous and fibrovascular tissue infiltration into
the porous scaffold, indicative of a rapid healing response and
penetration by native fibrovascular tissue by the two-month time point.
Reparative tissue growth within the Biomerix RCR Patch™ was
well-integrated into the tendon of the supraspinatus. - Results also indicated no signs of significant inflammation and scar tissue formation, indicative of a successful repair process in a challenging anatomic site
- In an ovine chronic supraspinatus tendon tear model, the Biomerix RCR Patch demonstrated statistically significant increases in failure force
(74%) and failure stress (95%) when compared to surgical control
animals at the three-month time point.2
1 Cole et al., “Biocompatibility of a polymer patch for rotator cuff repair,” Knee Surg Sports Tramatol Arthrosc (2007); 15(5):632-637.
2 1. Jost, B., et al. “Clinical outcomes after structural failure of rotator cuff repairs,” Journal of Bone and Joint Surgery — American edition (2000), 82:304-314.
Data on file with manufacturer